Interaction | Reaction | Process     Data Page

Acid chlorides react with to moles of Grignard reagent to form (initially) ketones and then tert. alkoxide ions. The reaction is difficult to stop at the dialkyl ketone intermediate and so this reaction is not a good synthetic route to ketones.

Generic Organic reaction
RCOCl
  +  
RMgX
  +  
         
Reactant Page Go To Go To
Acid chloride (generic)     Reactions Using    Reactions Forming
Grignard reagent (generic)     Reactions Using    Reactions Forming
Diethylether Solvent    Reactions Using    Reactions Forming
3° Alkoxide ion (generic)     Reactions Using    Reactions Forming

Interaction, Reaction, Process defined as:
Multistep: LA/B mechanism
Strategic Bond Formation

© Mark R. Leach 1999 –

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