Interaction | Reaction | Process Data Page
The Tascher-Eschenmoser method for cleaving methyl esters involves the direct nucleophilic attack of (soft) iodide ion upon the (soft delta+) methyl function.
Carboxylate ion acts as the nucleofugal leaving group. Solvent is usually anhydrous pyridine.
Chapter 15: Addition to carbon-carbon multiple bonds. J.March, Advanced Organic Chemistry, J. Wiley & Sons, Third Edition, 1985
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