Interaction | Reaction | Process     Data Page

Isocyanates are made in high yield by reacting primary amines with phosgene. Two moles of HCl are formed.
R–NH2
  +  
         
R–N=C=O
  +  
2
HCl
Reactant Page Go To Go To
1° Amine (generic)     Reactions Using    Reactions Forming
Phosgene     Reactions Using    Reactions Forming
Isocyanate (generic)     Reactions Using    Reactions Forming
Hydrogen chloride     Reactions Using    Reactions Forming

Interaction, Reaction, Process defined as:
Multistep: LA/B mechanism
Substitution: Nucleophilic Second Order

© Mark R. Leach 1999 –

Queries, Suggestions, Bugs, Errors, Typos...

If you have any:

Queries
Comments
Suggestions
Suggestions for links
Bug, typo or grammatical error reports about this page,

please contact Mark R. Leach, the author, using mark@meta-synthesis.com